This general information chapter Apparent Intrinsic Dissolution Testing Procedures for Rotating Disk and Stationary Disk 1087 discusses the determination of dissolution rates from nondisintegrating compacts exposing a fixed surface area to a given solvent medium. Compact, as used here, is a nondisintegrating mass resulting from compression of the material under test using appropriate pressure conditions. A single surface having specified physical dimensions is presented for dissolution. Determination of the rate of dissolution can be important during the course of the development of new chemical entities because it sometimes permits prediction of potential bioavailability problems and may also be useful to characterize compendial articles such as excipients or drug substances. Intrinsic dissolution studies are characterization studies and are not referenced in individual monographs. Information provided in this general information chapter is intended to be adapted via a specific protocol appropriate to a specified material.
Dipl. -Ing. Hans Anthony, ST
He was born in Dabo Singkep, Riau in 1987. He completed his study by receiving his Dipl.-Ing and Bachelor of Engineering Degree in Pharmaceutical Engineering Department from Swiss German University. He was graduated with Cum-laude and his thesis is patent registered with the title 'Production of Pharmaceutical Hard Capsule Shell from Corn Starch'. He was appointed as the Managing Director of PT. Pharma Test Indonesia after finishing a complete training in Pharma Test Headquarter, Germany.
He was born in Sukabumi in 1988. He finished his study in Physical Instrumentation Department of University of Indonesia. Prior to joining PT. Pharma Test Indonesia, he has work experiences in several companies such as PT. Telkom Indonesia and PT. Airfast Indonesia. He has good personality and a hard worker. He joined PT. Pharma Test Indonesia in 2010 and has been attended the training in Pharma Test Headquarter in Germany.