Media degassing or “de-aeration”, pre-heating to a temperature of 37°C and absolutely precise gravimetric dispensing according to the recommendations and demanded for dissolution testing from the US FDA authorities are standard for the Pharma Test PT-DDS4 media preparation and degasing system. De-aeration is generally recommended to prevent the formation of bubbles on the dosage form surface, which may cause a variation in active dissolution rates, by virtue of surface obscuration.

• De-aeration and heating of approx. 24 liters of media at the same time
• Pre-heating of media; target temperature adjustable from 30 – 50°C
• Adjustable gravimetric dosing range: 250 – 5,000 g
• Adjustable volumetric dosing range: 250 – 5,000ml (optional)
• Online buffer mixing, adjustable buffer dosing range: 100 – 5,000g (optional)
• LC display and keypad to show and enter data, like product information, batch number, etc.
• Live information about the remaining tank volume; minimum 1 liter
• File up to 16 de-aeration procedures (methods)

• Dosing Accuracy: ±0.5% of selected volume - gravimetric method and ±0.8% of selected volume - volumetric method
• Tank Volume: Approx. 24 liter
• Dispensing Time: for 1 Liter Approx. 45 - 60 seconds
• De-aeration and Heating Time: 24 liters within approx. 30 - 45 minutes
• Display: LED backlit LCD, 320x240 pixels, 9" diagonal, approx. 90x120mm
• Data Entry: Alpha numerical keypad
• Method: Memory Store up to 16 methods
• Printer: Thermo printer, 24 characters